Friday, August 04, 2006

Why is Candida albicans resistant to antifungals?

The treatment of Candida albicans is becoming more of a struggle as resistance to the limited number of antifungal drugs increases. Studies at the University of Minnesota have found that a certain chromosomal state, anneuploidy and an isochormosome, were responsible for resistance to azoles, important ingredients in antifungals.



Aneuploidy and Isochromosome Formation in Drug-Resistant Candida albicans



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